Angewandte Chemie International Edition
© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Cover Picture: Ruthenium-Catalyzed Asymmetric Propargylic Substitution Reactions of Propargylic Alcohols with Acetone (Angew. Chem. Int. Ed. 47/2005)
Diruthenium complexes with optically active thiolate-bridged ligands promote the catalytic propargylic substitution of propargylic alcohols with acetone as the nucleophile. The use of novel chiral ligands bearing a phenyl ring that can engage in a π–π interaction with a phenyl ring of the ruthenium–allenylidene moiety lead to high enantioselectivities in these processes. For more details, see the Communication by Y. Nishibayashi and co-workers on page 7715 ff.
Also of Interest
In their Minireview on page 7674 ff., P. Vogel and S. R. Dubbaka describe how recent developments in the area of ligands and additives allow the cross-coupling of a large variety of reactants, including inexpensive and readily available sulfonyl chlorides.
Hydrogel nanoparticles are promising materials for nanotechnological and biotechnological applications. In their Review on page 7686 ff., L. A. Lyon and S. Nayak describe the advances made with these swellable materials.
Lithium Alkoxide Cubanes
A dimeric, doubly bridged complex in which Li4O4 cubane units are connected by a transition-metal complex is presented by D. A. Sweigart and co-workers in their Communication on page 7710 ff.