Angewandte Chemie International Edition

Cover image for Vol. 56 Issue 14

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

45_22/2006Cover Picture: Highly Enantioselective Aza-Baylis–Hillman Reaction in a Chiral Reaction Medium (Angew. Chem. Int. Ed. 22/2006)

Chiral solvents are capable of inducing high enantioselectivities in asymmetric reactions after all. Functionalized chiral ionic liquids are particularly suitable for this purpose as they can interact strongly (e.g., through electrostatic interactions and hydrogen bonding) with substrates and/or intermediates. W. Leitner and co-workers show in their Communication on page 3689 ff. that this concept can be used for the aza-Baylis–Hillman reaction to achieve products with up to 84% ee.

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In their Review on page 3584 ff., J. M. Shreeve et al. present recent developments in the field of nitrogen-rich energetic salts and ionic liquids. The properties of the corresponding molecular compounds are a benchmark for this emerging substance class.

Bioinorganic Chemistry Evidence for the formation of a nickel–carbon bond at the active site of the enzyme involved in the key step of methanogenesis is described by J. Harmer, B. Jaun, and co-workers in their Communication on page 3602 ff.for002

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In their Communication on page 3656 ff., R. G. Cooks et al. describe a method to generate gas-phase ions from a variety of organic salts, including ionic liquids and transition-metal salts, and perform ion–molecule reactions at atmospheric pressure.