Angewandte Chemie International Edition
© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Inside Cover: Rapid In Vivo Fingerprinting of Nonvolatile Compounds in Breath by Extractive Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometry (Angew. Chem. Int. Ed. 4/2007)
Metabolic dynamics can be followed in real time by mass spectral fingerprints of breath by extractive electrospray ionization (EESI) quadrupole TOF mass spectrometry on a commercial instrument. Neither sample pretreatment nor hardware modifications are necessary for this rapid, online, and in vivo method. Furthermore, selective ion/molecule reactions in the EESI interface can lead to the detection of interesting compounds. For more details see the Communication by R. Zenobi and co-workers on page 580ff.