Angewandte Chemie International Edition

Cover image for Vol. 55 Issue 27

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPlusChem, Zeitschrift für Chemie

46_14/2007Cover Picture: Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligodipeptides and Oligodipeptoids Tagged with Triazines as Recognition Elements / Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligodipeptides Tagged with 2,4-Disubstituted 5-Aminopyrimidines as Recognition Elements (Angew. Chem. Int. Ed. 14/2007)

2,4-Dioxo- and 2,4-diamino derivatives of the 5-aminopyrimidine nucleus, which are attached to an oligodipeptide backbone, display inverse base-pairing strengths with complementary DNA and RNA compared to the corresponding 2,4-diamino- and 2,4-dioxotriazine derivatives. In their Communications on pages 2470 and 2478 ff., R. Krishnamurthy, A. Eschenmoser, and co-workers point to a remarkable correlation between pairing strength and ΔpKa values of pairs of complementary bases.

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Also of Interest

Supramolecular Chemistry in Waterfor001

The Review by W. Verboom et al. on page 2366 ff. focuses on the formation and reactivity of supramolecular aggregates in aqueous media. Such media are the environments in which natural self-assembly processes occur.


In their Communication on page 2394 ff., J. L. Atwood and R. M. McKinlay demonstrate the assembly of six calix[4]arene molecules by hydrogen bonding. The observed toroidal shape represents an exceptional topology for noncovalent assemblies.

Metal-Storage Proteinsfor003

The cavity shell of a molybdenum/tungsten-storage (Mo/WSto) protein acts as a polytopic host for noncovalently or weakly bonded polyoxotungstate guests. A. Müller, U. Ermler, and co-workers discuss this “biological supramolecular chemical system” in their Communication on page 2408 ff.