Angewandte Chemie International Edition
Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Inside Cover: Facile Preparation of Complex Protein Architectures with Sub-100-nm Resolution on Surfaces (Angew. Chem. Int. Ed. 36/2007)
Multiple proteins are simultaneously patterned into complex architectures by a novel method, as reported by E. Delamarche and co-workers in their Communication on page 6837 ff. This method involves three elementary steps: inking of proteins onto an elastomer, subtracting the proteins to form a pattern by using a nanotemplate, and printing the remaining proteins onto the substrate. Combining and repeating these steps allows the patterning of proteins on surfaces with arbitrary patterns and a resolution better than 100 nm.