Angewandte Chemie International Edition
Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Inside Cover: Shining New Light on an Old Problem: Retooling MALDI Mass Spectrometry for Organotransition-Metal Catalysis (Angew. Chem. Int. Ed. 2/2008)
Inert-atmosphere MALDI-MS is a powerful new tool for identifying organometallic compounds. As described by D. E. Fogg and co-workers in the Communication on page 303 ff., sample decomposition is minimized by interfacing the spectrometer to a glovebox and ionizing by charge transfer. Neutral compounds, such as the Grubbs-class catalyst shown, are observed as radical cations. The metal isotope patterns expand the utility and scope of this methodology in transition-metal chemistry.