Angewandte Chemie International Edition

Cover image for Vol. 56 Issue 43

Editor: Neville Compton; Editor Emeritus: Peter Gölitz

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

47_09b/2008Inside Cover: The Structure of the Neuropeptide Bradykinin Bound to the Human G-Protein Coupled Receptor Bradykinin B2 as Determined by Solid-State NMR Spectroscopy (Angew. Chem. Int. Ed. 9/2008)

The structure of the neuropeptide bradykinin bound to the human G-protein-coupled bradykinin subtype 2 receptor has been determined by solid-state NMR spectroscopy. As described by C. Glaubitz and co-workers in their Communication on page 1668 ff., its elongated conformation comprises an α-helical turn at the N terminus and a β turn at the C terminus. This structure offers, for the first time, an experimental template for tailored drug design for this human GPCR.

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