Angewandte Chemie International Edition

Cover image for Vol. 56 Issue 31

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

47_15/2008Cover Picture: Exogenous Agents that Target Transmembrane Domains of Proteins (Angew. Chem. Int. Ed. 15/2008)

Molecular recognition in protein transmembrane domains is little understood because of the lack of suitable probes with high affinity and specificity. The recent development of exogenous agents that can recognize protein transmembrane domains are described by H. Yin in the Minireview on page 2744 ff. The cover picture is an artist's representation of a computed helical anti-membrane protein (CHAMP) peptide associating with a transmembrane domain of integrin αIIbβ3. These studies have laid the groundwork for targeting protein–protein interactions in the membrane. (Original artwork: Barbara Seymour.)

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Also of Interest

Liquid Crystalsfor001

J. W. Goodby et al. give an alternative view of liquid crystals in their Review on page 2754 ff. They show that molecules certainly do not need to be rod or disc shaped to form liquid-crystalline phases.

Heterogeneous Catalysisfor002

In their Communication on page 2788 ff. D. J. Buttrey and co-workers show how the use of aberration-corrected STEM imaging allows direct visualization of the orthorhombic M1 phase primary component of the MoVNbTeO propane ammoxidation catalyst.

Single-Molecule Magnetsfor003

Crystallographic studies reported by E. K. Brechin, S. Parsons and co-workers in their Communication on page 2828 ff. show the drastic structural changes that occur in the core of a Mn6 single-molecule magnet under high pressure. These changes greatly influence the magnetic properties.