Angewandte Chemie International Edition
© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Cover Picture: Carboxylic Acids as Substrates in Homogeneous Catalysis (Angew. Chem. Int. Ed. 17/2008)
The rich chemistry of carboxylic acids as substrates in transition-metal catalysis has evolved in recent years. It is the key for developing new, more sustainable organic transformations from renewable raw materials. The cover picture shows the large number of different product classes accessible by catalytic transformations of carboxylic acids, emphasizing their high synthetic potential. In their Review on page 3100 ff., L. J. Gooßen et al. provide an overview of this emerging field offering extensive research possibilities.
Also of Interest
In their Review on page 3122 ff., F. E. Hahn and M. C. Jahnke present the advances in the synthetic and coordination chemistry of heterocyclic carbenes. Variation of the substitution patterns and heteroatoms is now possible and allows control of the properties of these compounds.
W. J. Buma et al. show in their Communication on page 3174 ff. that the conformation of flexible molecules can be controlled by enclosing them in a molecular mold, and then, after rapid cooling, releasing them with a laser pulse.
Rhodium amide complexes can catalyze the transfer hydrogenation of ketones and activated olefins using ethanol as hydrogen donor. As H. Grützmacher et al. show in their Communication on page 3245 ff., only mild conditions are required to give the corresponding alcohols and ethyl acetate.