Angewandte Chemie International Edition
Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Cover Picture: A Highly Emissive Fluorescent Nucleoside that Signals the Activity of Toxic Ribosome-Inactivating Proteins (Angew. Chem. Int. Ed. 35/2008)
Ribosome-inactivating proteins, ... such as ricin, are among the most poisonous toxins known. Despite their simple isolation from natural sources (shown is Ricinus communis, or castor bean plant), there is a lack of useful therapeutics or field detection tools. In their Communication on page 6661 ff. Y. Tor et al. describe RNA constructs that are complementary to the α-sarcin/ricin RNA substrate and signal the depurination of a specific adenosine residue. (Picture source: O. T. Thomé, Flora von Deutschland, Österreich und der Schweiz, 1885, Gera.)
Also of Interest
Devices using semiconductor nanocrystals as emitters have great potential as light-emitting diodes. The fabrication and the performance of these devices is discussed by A. Eychmüller et al. in their Review on page 6538 ff.
Carbon nanotubes (CNTs) are highly sensitive to changes in their chemical environment, which makes them ideal candidates for chemical sensors. In the Review on page 6550 ff., A. Star and D. R. Kauffman describe current research on CNT sensors for gas-phase analytes.
In their Communication on page 6571 ff. Z. Qiu and Z. Xie describe a cross-coupling reaction between nickel carboryne and a range of alkenes. The reactions proceed with excellend regio- and stereoselectivity.