Angewandte Chemie International Edition
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Inside Cover: An Interrupted [4+3] Cycloaddition Reaction: A Hydride Shift (Ene Reaction) Intervenes (Angew. Chem. Int. Ed. 45/2008)
Chemistry is the study of how atoms and molecules interact and react with each other. Often we can predict and control outcomes; on other occasions nature leads us down an unexpected path, which can lead to the discovery of new or better chemical processes. In the Communication on page 8696 ff., M. Harmata, P. R. Schreiner, and co-workers describe how they were directed away from a [4+3] cycloaddition down a road leading toward an ene reaction of oxyallylic cations that is both synthetically useful and fundamentally interesting.