Angewandte Chemie International Edition

Cover image for Vol. 55 Issue 31

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPlusChem, Zeitschrift für Chemie

48_06/2009Cover Picture: Nickel α-Keto-β-Diimine Initiators for Olefin Polymerization (Angew. Chem. Int. Ed. 6/2009)

Modification of a ligand framework by the introduction of an exocyclic carbonyl group (highlighted in red) results in a remarkable increase in the activity of a nickel olefin polymerization catalyst. As described by G. C. Bazan and co-workers in the Communication on page 1089 ff., the oxygen lone pairs allow Lewis acids to withdraw electron density from the cationic active site. Such modulation of electronic effects allows the reactivity of electrophilic transition-metal active sites to be tuned.

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Also of Interest

Oral Protein Deliveryfor001

How can peptide and protein drugs be administered orally without their hydrolysis in the stomach? R. P. Doyle, T. J. Fairchild, and A. K. Petrus propose a solution in their Minireview on page 1022 ff.: Conjugation to vitamin B12 enables the use of an existing dietary uptake pathway.

Two-Dimensional Polymersfor002

How can a truly two-dimensional polymer be produced? A. D. Schlüter et al. describe in their Review on page 1030 the strategies used to date and analyze the prerequisites for a successful synthesis.

Synthetic Methodsfor003

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