Angewandte Chemie International Edition
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Inside Cover: Mechanical Nanosensor Based on FRET within a Thermosome: Damage-Reporting Polymeric Materials (Angew. Chem. Int. Ed. 31/2009)
An engineered hybrid protein assembly that is embedded in a polymer acts as a sensor for structural deformation of the matrix. In their Communication on page 5666 ff., D. S. Clark and co-workers report the encapsulation of a FRET pair of fluorescent proteins into a chaperonin. The protein hybrid was copolymerized with a monomer to produce a self-reporting material. Damage is reported by a change in the fluorescence signal when the material is mechanically stressed.