Angewandte Chemie International Edition

Cover image for Vol. 55 Issue 41

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPlusChem, Zeitschrift für Chemie

49_17b/2010Inside Cover: Sensitive Detection of Native Proteins Using Extractive Electrospray Ionization Mass Spectrometry (Angew. Chem. Int. Ed. 17/2010)

Characterization of native proteins can be undertaken with extractive electrospray ionization mass spectrometry (EESI-MS). As H. Chen and co-workers describe in their Communication on page 3053 ff., EESI deposits charges on native proteins, which are separated from any high electric field. This method facilitates mass spectrometry, even from raw biological samples, without significant conformational changes or reduction in activity.

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