Angewandte Chemie International Edition

Cover image for Vol. 56 Issue 40

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

49_23b/2010Inside Cover: Chemical Proteomics Discloses Petrosapongiolide M, an Antiinflammatory Marine Sesterterpene, as a Proteasome Inhibitor (Angew. Chem. Int. Ed. 23/2010)

Petrosaspongiolide M, a marine natural product with anti-inflammatory properties, has an intriguing pharmacological profile. In their Communication on page 3960 ff. Casapullo and co-workers identified the macromolecular targets of this potential drug candidate; the 20S proteasome was found to be its most important target.

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