Angewandte Chemie International Edition

Cover image for Vol. 56 Issue 19

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

49_47b/2010Inside Cover: A Potent Trans-Diimine Platinum Anticancer Complex Photoactivated by Visible Light (Angew. Chem. Int. Ed. 47/2010)

Photoactivation can be used to activate anticancer drugs selectively just at the site of a tumor. Such targeted treatments promise fewer side effects and may address the problem of acquired resistance associated with drugs such as cisplatin. P. J. Sadler and co-workers show in their Communication on page 8905 ff. that the octahedral complex trans,trans,trans-[PtIV(N3)2(OH)2(py)2] is potentially cytotoxic towards a number of cell lines when activated by blue light, with no toxicity in the absence of irradiation.

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