Angewandte Chemie International Edition
© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Inside Cover: Design of a Three-Helix Bundle Capable of Binding Heavy Metals in a Triscysteine Environment (Angew. Chem. Int. Ed. 9/2011)
A three-helix bundle having a well-defined metal coordination geometry has been prepared. V. L. Pecoraro and co-workers describe, in their Communication on page 2049 ff., the ability to obtain well-defined structures among a myriad of different possible folds. The metal–ligand bonds result in a well-folded and stable protein that encapsulates heavy metals.