Angewandte Chemie International Edition

Cover image for Vol. 56 Issue 31

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

50_18/2011Cover Picture: Micromachine-Enabled Capture and Isolation of Cancer Cells in Complex Media (Angew. Chem. Int. Ed. 18/2011)

Antibody-functionalized microengine rockets can selectively capture and transport pancreatic cancer cells in complex biological media. In their Communication on page 4161 ff., Zhang, Wang, and co-workers report that these microrockets recognize individual cancer cells from a cell mixture with high selectivity. This strategy holds promise for the design of bioanalytical protocols and microchip devices for early-stage tumor cell detection.

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Also of Interest

Natural Product Synthesisfor001

In their Review on page 4068 ff., J. A. Porco, Jr. and S. P. Roche discuss a new dimension in natural product chemistry. Dearomatization processes can be used to convert planar aromatic intermediates into the three-dimensional frameworks of complex natural products.

Supramolecular Networksfor002

In their Communication on page 4094 ff., F. Cherioux et al. present STM images of a large 2D open supramolecular framework with an unusually high resolution of both the silicon substrate and the molecular network at room temperature.

MRI Contrast Agentsfor003

R. D. Tilley et al., describe in their Communication on page 4206 ff. how small tumors can be visualized in a facile way with the help of strongly magnetic iron core/iron oxide shell nanoparticles.