Angewandte Chemie International Edition
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Back Cover: An Additional Coordination Group Leads to Extremely Efficient Chiral Iridium Catalysts for Asymmetric Hydrogenation of Ketones (Angew. Chem. Int. Ed. 32/2011)
Highly efficient chiral catalysts for asymmetric hydrogenation have always been a central issue in both academic and industrial research. In their Communication on page 7329 ff., J.-H. Xie, Q.-L. Zhou, and co-workers describe a new strategy for inhibiting the deactivation of chiral iridium catalysts by introducing an additional coordination group. This strategy led to the discovery of an exceptionally active and highly enantioselective chiral iridium catalyst for ketone hydrogenation.