Angewandte Chemie International Edition

Cover image for Vol. 55 Issue 31

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPlusChem, Zeitschrift für Chemie

50_42/2011Cover Picture: Bond Activation with an Apparently Benign Ethynyl Dithiocarbamate Ar-C≡C-S-C(S)NR2 (Angew. Chem. Int. Ed. 42/2011)

A hedgehog molecule activates a variety of bonds. In their Communication on page 9923 ff., G. Bertrand et al. report that an ethynyl dithiocarbamate molecule, Ar-C≡C-S-C(S)NR2 (hedgehog on the bottom left), is able to cleave a broad range of enthalpically strong σ bonds. The bond activation process involves either the existence of an equilibrium with the nonobservable cyclic mesoionic carbene isomer or the cooperation of the nucleophilic carbon–carbon triple bond and the electrophilic CS carbon atom, both leading to cyclic products (hedgehogs in the wheel).

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Also of Interest

C-H Functionalizationfor001

Deprotonation of (hetero)aromatic compounds can be achieved with LiCl-solubilized metal amide bases. The resulting metalated intermediates can be functionalized by reactions with electrophiles, as reported by P. Knochel et al. in their Review on page 9794 ff.

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