Angewandte Chemie International Edition

Cover image for Vol. 55 Issue 44

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPlusChem, Zeitschrift für Chemie

51_09i/2012Inside Cover: A Synthetic Approach Toward a Self-Regulated Insulin Delivery System (Angew. Chem. Int. Ed. 9/2012)

A totally synthetic artificial pancreas is described by Y. Miyahara et al. in their Communication on page 2124 ff. A hydrogel bearing a phenylboronate derivative undergoes a glucose-dependent transition in its state of hydration under physiological conditions. The reversible surface-localized dehydration enables the provision of insulin to be controlled, thus offering a new basis for the treatment of diabetes with long-term stability and safety.

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