Angewandte Chemie International Edition
© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Cover Picture: Oligoprolines as Scaffolds for the Formation of Silver Nanoparticles in Defined Sizes: Correlating Molecular and Nanoscopic Dimensions (Angew. Chem. Int. Ed. 17/2012)
Functionalized oligoproline scaffolds that have defined lengths have been shown to control the size of silver nanoparticles that are formed in the Tollens reaction. In their Communication on page 4231 ff., H. Wennemers et al. demonstrate the correlation between the molecular dimensions of the peptide scaffold and the size of the nanoparticles that are produced in an approach that opens the door to precise control of the size of metal nanoparticles.
Also of Interest
In their Communication on page 4046 ff., M. T. Stubbs et al. show that TobZ, responsible for the biotransformation of the antibiotic tobramycin to nebramycin 5', catalyzes a two-step reaction via an essential carbamoyladenylate intermediate.
In their Communication on page 4204 ff., K. D. Janda et al. describe a series of 4,5-dihydroxy-2,3-pentanedione structural isomers and discuss the implications of these isomers for bacterial communication.
The first step of the biosynthesis of the antibiotic moenomycin is catalyzed by the prenyltransferase MoeO5, which has a triose-phosphate-isomerase barrel structure, as E. Oldfield, R.-T. Guo et al. show in their Communication on page 4157 ff.