Angewandte Chemie International Edition

Cover image for Vol. 55 Issue 19

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPlusChem, Zeitschrift für Chemie

51_17c/2012Inside Back Cover: Uncharacterized 4,5-Dihydroxy-2,3-Pentanedione (DPD) Molecules Revealed Through NMR Spectroscopy: Implications for a Greater Signaling Diversity in Bacterial Species (Angew. Chem. Int. Ed. 17/2012)

4,5-Dihydroxy-2,3-pentanedione (DPD) is the common precursor of the autoinducer-2 class of bacterial quorum sensing molecules. DPD has been proposed as a universal signaling molecule between Gram-positive and Gram-negative bacteria. In their Communication on page 4204 ff., K. D. Janda and co-workers uncover a complex array of DPD structural isomers, which suggests that the bacterial lexicon may be larger than previously thought. (Detective image copyright Martin Malchev/

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