Angewandte Chemie International Edition

Cover image for Vol. 53 Issue 30

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, Zeitschrift für Chemie

51_19b/2012Back Cover: Sensitive and High-Throughput Isolation of Rare Cells from Peripheral Blood with Ensemble-Decision Aliquot Ranking (Angew. Chem. Int. Ed. 19/2012)

A blood sample was broken up into nanoliter volumes, and subsequently each aliquot was ranked based on whether or not a rare cell was present in the ensemble of cells within the aliquot. This approach is called ensemble decision aliquot ranking (eDAR). In their Communication on page 4618 ff., D. T. Chiu et al. show that the eDAR technique is well-suited for the enrichment of rare cells, such as circulating tumor cells.

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