Angewandte Chemie International Edition
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Cover Picture: Silicon Nanowires as Photoelectrodes for Carbon Dioxide Fixation (Angew. Chem. Int. Ed. 27/2012)
Photofixation of CO2 to produce synthetically valuable molecules can be achieved on a photoelectrode based on silicon nanowires. In their Communication on page 6709 ff., K. L. Tan, D. Wang et al. develop a strategy that uses aromatic ketones to receive the photogenerated electrons. The resulting radicals then react with carbon dioxide to afford α-hydroxy acids, which are precursors for the drugs ibuprofen and naproxen. In close resemblance to natural photosynthesis, their strategy gains reaction specificity by avoiding the direct reduction of CO2.
Also of Interest
Aurora kinase A (AKA) plays a key role in mitosis. In their Communication on page 6598 ff., R. Weissleder and co-workers show how AKA can be imaged in live cells using an florescent reporter and an AKA inhibitor.
Vitamin B12 A new facet in the chemistry of vitamin B12 has been discovered by B. Kräutler et al. On page 6780 ff., they report the efficient reductive ring closure of a secocorrinoid to reconstitute the macrocycle of vitamin B12.