Angewandte Chemie International Edition

Cover image for Vol. 56 Issue 14

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

51_44b/2012Back Cover: Ceria Nanoparticles that can Protect against Ischemic Stroke (Angew. Chem. Int. Ed. 44/2012)

Ceria nanoparticles are known to exhibit free-radical scavenging activity by reversibly binding oxygen. In their Communication on page 11039 ff., S.-H. Lee, T. Hyeon, et al. show that discrete, uniform 3 nm PEGylated ceria nanoparticles can protect against ischemic stroke by scavenging reactive oxygen species and reducing apoptosis. Optimal doses of ceria nanoparticles reduce infarct volumes and the rate of ischemic cell death, and target the infarct site in vivo.

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