Angewandte Chemie International Edition
© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Inside Back Cover: Accelerated Carbon-Carbon Bond-Forming Reactions in Preparative Electrospray (Angew. Chem. Int. Ed. 47/2012)
Mass spectrometry is a new tool for microscale synthesis. In their Communication on page 11832 ff., T. Müller, A. Badu-Tawiah, and R. G. Cooks show that the carbon–carbon bond-forming Claisen–Schmidt condensation occurs at dramatically increased rates and gives high yields when the reactants are electrosprayed online into a mass spectrometer or offline onto a high-surface-area substrate.