Angewandte Chemie International Edition
© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Cover Picture: Heterolytic Activation of H2 Using a Mechanically Interlocked Molecule as a Frustrated Lewis Base (Angew. Chem. Int. Ed. 3/2013)
The reactivity of frustrated Lewis pairs is induced by the utilization of a sterically unencumbered aniline as the axle in a rotaxane. In their Communication on page 960 ff., S. J. Loeb, D. W. Stephan, and co-workers show that the rotaxane imparts enough steric bulk to the base to preclude adduct formation with B(C6F5)3. This unique modification also shows frustrated Lewis pair reactivity in the activation of H2 at room temperature.
Also of Interest
Light-Triggered Chemical Biology
R. Tampé and co-workers describe in their Communication on page 848 ff. photoactivatable multivalent tetracysteine derivatives for the in situ labeling and assembly of His-tagged proteins in time and space.
Controlled Cargo Release
In their Communication on page 1008 ff., A. Herrmann and co-workers describe a method for sequence-specific cargo release from DNA-encoded lipid vesicles through the stable tagging of the liposome surface with amphiphilic DNA block copolymers.
A diatom species was found to employ sophisticated pheromone chemistry to locate mature sexual partners. In their Communication on page 854 ff., G. Pohnert et al. describe the metabolome of Seminavis robusta.