Angewandte Chemie International Edition
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Cover Picture: Complexity from Simplicity: Tricyclic Aziridines from the Rearrangement of Pyrroles by Batch and Flow Photochemistry (Angew. Chem. Int. Ed. 5/2013)
Complex tricylic aziridines can be prepared from simple pyrroles by UV irradiation. In their Communication on page 1499 ff., K. I. Booker-Milburn and co-workers show that the reaction proceeds by a two-stage photochemical sequence that involves [2+2] cycloaddition and rearrangement, and that the scale of the reaction can be increased using a customized FEP flow reactor.
Also of Interest
A photocleavable linker was used to connect insulin with an insoluble resin. In their Communication on page 1404 ff., S. H. Friedman et al. show that light pulses can be used to release insulin in a controlled fashion.
In their Communication on page 1494 ff., S. V. Ovsyannikov et al. describe a new perovskite-like structure for Mn2O3, prepared under high-temperature high-pressure conditions. This structure contains Mn in three oxidation states within a distorted octahedral framework.
D. Söll et al. describe in their Communication on page 1441 ff. a synthetic tRNA that is accepted by the E. coli ribosome. This selenocysteine tRNA can be incorporated site-specifically into proteins to study their function.