Angewandte Chemie International Edition
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Back Cover: A Structured Monodisperse PEG for the Effective Suppression of Protein Aggregation (Angew. Chem. Int. Ed. 9/2013)
Poly(ethylene glycol) (PEG) with a discrete triangular structure exhibits hydrophilicity/hydrophobicity switching at a lower temperature than the corresponding linear PEG. In their Communication on page 2430 ff, T. Muraoka, K. Kinbara, and co-workers report that such a triangular PEG analogue helps lysozyme preserve the higher order structure at high temperatures and efficiently suppresses its thermal aggregation.