Angewandte Chemie International Edition

Cover image for Vol. 54 Issue 50

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPlusChem, Zeitschrift für Chemie

52_09i/2013Inside Cover: Access to Organometallic Arylcobaltcorrins through Radical Synthesis: 4-Ethylphenylcobalamin, a Potential “Antivitamin B12” (Angew. Chem. Int. Ed. 9/2013)

An organometallic arylcobalamin is a “locked” form of vitamin B12 or “antivitamin B12”, and is accessible by a radical reaction, as reported by B. Kräutler et al. in their Communication on page 2606 ff. “Antivitamins B12” are novel molecular tools to induce functional vitamin B12 deficiency in laboratory animals. These studies may be helpful in clarifying controversial questions dealing with irreparable damage in the central and peripheral nervous system that is associated with vitamin B12 deficiency in humans.

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