Angewandte Chemie International Edition

Cover image for Vol. 54 Issue 27

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPlusChem, Zeitschrift für Chemie

52_11/2013Cover Picture: Expression of Fluorescent Cyclotides using Protein Trans-Splicing for Easy Monitoring of Cyclotide–Protein Interactions (Angew. Chem. Int. Ed. 11/2013)

Cyclotides are natural microproteins found in plants with a head-to-tail circular Cys-knotted topology. In their Communication on page 3126 ff., J. A. Camarero et al. show the recombinant production of a fluorescently labeled cyclotide inside live bacterial cells. Grown in the presence of p-azidophenylalanine and a dibenzocyclooctyne derivative of the fluorescent dye aminomethylcoumarin acetate (AMCA) the peptide is labeled in vivo. Cover art: Isaac Mora.

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Also of Interest

Cyclotides are natural microproteins found in plants with a head-to-tail circular Cys-knotted topology. In their Communication on page 3126 ff., J. A. Camarero et al. show the recombinant production of a fluorescently labeled cyclotide inside live bacterial cells. Grown in the presence of p-azidophenylalanine and a dibenzocyclooctyne derivative of the fluorescent dye aminomethylcoumarin acetate (AMCA) the peptide is labeled in vivo. Cover art: Isaac Mora.

Oxygen Reduction Reactionfor001

B/N-doped graphene shows a synergistic effect that boosts its catalytic activity for oxygen reduction. The excellent catalytic performance of the new metal-free catalyst is comparable to that of commercial Pt/C, as explained by S. Z. Qiao et al. in their Communication on page 3110 ff.


Molecular Dynamicsfor002

The Coulombic explosion of a uracil molecule, set off by an ionized water molecule, is studied by M.-A. Hervé du Penhoat, M.-F. Politis, et al. in their Communication on page 3160 ff. They used molecular dynamics methods to investigate the influence of ionizing radiation on DNA.


Supramolecular Assemblyfor003

Underwater adhesion between two surfaces was produced using the host–guest binding pair of cucurbit[7]uril and aminomethylferrocene. In their Communication on page 3140 ff., K. Kim et al. demonstrate the strength and reversibility of this supramolecular velcro.


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