Angewandte Chemie International Edition

Cover image for Vol. 57 Issue 4

Editor: Neville Compton, Deputy Editor: Frank Maass. Editor Emeritus: Peter Gölitz

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

52_14b/2013Back Cover: Supramolecular Control of Selectivity in Hydroformylation of Vinyl Arenes: Easy Access to Valuable β-Aldehyde Intermediates (Angew. Chem. Int. Ed. 14/2013)

Precise selectivity control in transition-metal catalysis is critical for modern chemical synthesis. In their Communication on page 3878 ff., J. N. H. Reek and P. Dydio demonstrate that substrate preorganization through noncovalent supramolecular interactions with the ligand is a powerful enabling strategy to control selectivity, and gives access to usually unfavored products. As exemplified for the Rh-catalyzed hydroformylation of vinyl arenes, this approach opens up new avenues in the synthesis of valuable compounds.

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