Angewandte Chemie International Edition

Cover image for Vol. 54 Issue 18

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPlusChem, Zeitschrift für Chemie

52_21c/2013Inside Back Cover: High-Throughput Screening for Terpene-Synthase-Cyclization Activity and Directed Evolution of a Terpene Synthase (Angew. Chem. Int. Ed. 21/2013)

Active terpene synthase mutants are generally identified by using lower-throughput GC-based methods. In their Communication on page 5571 ff., F. H. Arnold and co-workers describe a terpene synthase substrate that enables cyclization activity to be screened in a high-throughput manner. The screening protocol allows the identification of active mutants by the brilliant purple color that these mutants generate in the assay.

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