Angewandte Chemie International Edition

Cover image for Vol. 53 Issue 39

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPlusChem, Zeitschrift für Chemie

53_04/2014Cover Picture: Neurotrophic Natural Products: Chemistry and Biology (Angew. Chem. Int. Ed. 4/2014)

The human brain is an incredibly complex network of neurons that controls life, thoughts, and emotion. Age- or disease-related neural degeneration leads to breakdown of this network, incapacitating the affected individual. Certain natural products can induce outgrowth of neurites, the bridges that allow cell–cell communication in the brain, and so restore the neuronal web. E. A. Theodorakis et al. summarize in their Review on page 956 ff. recent advances in the synthesis of these molecules and highlight their potential as tools for studying neuronal web structure and function.

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The human brain is an incredibly complex network of neurons that controls life, thoughts, and emotion. Age- or disease-related neural degeneration leads to breakdown of this network, incapacitating the affected individual. Certain natural products can induce outgrowth of neurites, the bridges that allow cell–cell communication in the brain, and so restore the neuronal web. E. A. Theodorakis et al. summarize in their Review on page 956 ff. recent advances in the synthesis of these molecules and highlight their potential as tools for studying neuronal web structure and function.

Affinity Pairsfor001

In their Communication on page 988 ff., K. Mlinarić-Majerski, R. Glaser, L. Isaacs, et al. report the formation of an exceptionally tight noncovalent complex between cucurbit[7]uril and a diamantane diammonium ion in pure D2O.


Zeolitesfor002

A cobalt-containing zeolitic imidazolate framework that functions as a co-catalyst for the reduction of CO2 in the presence of a ruthenium photosensitizer is described by X. Wang and co-workers in their Communication on page 1034 ff.


Dynamic Porous Materialsfor003

P. Sozzani et al. demonstrate in their Communication on page 1043 ff., that low-density, yet robust covalent architectures can sustain extremely rapid rotational motion of phenylene rings.


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