Angewandte Chemie International Edition

Cover image for Vol. 56 Issue 28

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

53_11i/2014Inside Cover: Inhibition of Heme Uptake in Pseudomonas aeruginosa by its Hemophore (HasAp) Bound to Synthetic Metal Complexes (Angew. Chem. Int. Ed. 11/2014)

The secreted heme acquisition protein of P. aeruginosa (HasAp), which is shaped like a fish, was found to be able to capture various synthetic iron complexes, such as iron–salophen and iron–phthalocyanine. In their Communication on page 2862 ff., O. Shoji, Y. Watanabe, and co-workers demonstrate the effect of HasAp bound to these unnatural iron complexes on the growth of P. aeruginosa and show that HasAp bound to iron–phthalocyanine inhibits HasAp-mediated iron acquisition.

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