Angewandte Chemie International Edition

Cover image for Vol. 57 Issue 9

Editor: Neville Compton, Deputy Editor: Frank Maass. Editor Emeritus: Peter Gölitz

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

53_15/2014Cover Picture: Interaction with the Surrounding Water Plays a Key Role in Determining the Aggregation Propensity of Proteins (Angew. Chem. Int. Ed. 15/2014)

Interaction with the surrounding water was shown to play a crucial role in determining the aggregation propensity of proteins. In their Communication on page 3961 ff., S.-H. Chong and S. Ham shown that the overall protein hydrophobicity, defined by the hydration free energy of the protein, is the predominant determinant of protein aggregation propensity in aqueous solutions. This result paves the way for the design of aggregation-resistant proteins as biotherapeutics.

Read Full Text  | Table of Contents

Also of Interest

Interaction with the surrounding water was shown to play a crucial role in determining the aggregation propensity of proteins. In their Communication on page 3961 ff., S.-H. Chong and S. Ham shown that the overall protein hydrophobicity, defined by the hydration free energy of the protein, is the predominant determinant of protein aggregation propensity in aqueous solutions. This result paves the way for the design of aggregation-resistant proteins as biotherapeutics.

Antimicrobial Polymersfor001

The antibacterial activity of a polymer can be controlled by a bio-cleavable satellite group. In their Communication on page 3830 ff. J. C. Tiller et al., report that a antimicrobial polymer can be deactivated by a lipase-catalyzed hydrolysis of an ester group.


Wireless Electrodepositionfor002

In their Communication on page 4001 ff., A. Kuhn, D. Bradshaw, et al. describe a high-spatial-control synthesis of Janus metal–organic frameworks without the need for a physical connection between the modified object and the electrode.


Prussian Blue Nanoparticlesfor003

A new method for the synthesis of core–shell gold@Prussian blue analogue nanoparticles that exhibit plasmonic and magnetic properties is described by Y. Guari and co-workers in their Communication on page 3872 ff.


SEARCH

SEARCH BY CITATION