Angewandte Chemie International Edition

Cover image for Vol. 53 Issue 32

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, Zeitschrift für Chemie

53_19/2014Cover Picture: A New Pathway of DNA G-Quadruplex Formation (Angew. Chem. Int. Ed. 19/2014)

Guanine-rich DNA sequences can self-assemble into specific pre-organized DNA structures, where two-by-two guanine residues shown as “duets” are involved in GG N1-carbonyl symmetric base pairs. In their Communication on page 4881 ff., J. Lah, J. Plavec, and co-workers demonstrate the transition of these “duets” into guanine-quartets, presented as a “string quartet” when interacting with cations, such as potassium ions. This rearrangement consequently leads to formation of G-quadruplex structures.

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Also of Interest

Guanine-rich DNA sequences can self-assemble into specific pre-organized DNA structures, where two-by-two guanine residues shown as “duets” are involved in GG N1-carbonyl symmetric base pairs. In their Communication on page 4881 ff., J. Lah, J. Plavec, and co-workers demonstrate the transition of these “duets” into guanine-quartets, presented as a “string quartet” when interacting with cations, such as potassium ions. This rearrangement consequently leads to formation of G-quadruplex structures.

Aptamer Screeningfor001

A new particle display method for aptamer screening is described by H. T. Soh and co-workers in their Communication on page 4796 ff. High-quality aptamers can be generated rapidly and economically by this approach.


Oligomer Growthfor002

In their Communication on page 4872 ff., T. J. Meyer et al. describe that ruthenium(II) vinylpolypyridyl complexes can be grown within the cavities of TiO2 films by electrochemically controlled radical polymerization.


Carbaporphyrinoidsfor003

L. Latos-Grażyński and co-workers describe in their Communication on page 4885 ff., the synthesis of 21-carbathiaporphyrin, the first meso-substituted true carbaporphyrin with an unsubstituted cyclopentadienyl moiety.


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