Angewandte Chemie International Edition

Cover image for Vol. 56 Issue 35

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

53_24b/2014Back Cover: Sequential Intra-Intercellular Nanoparticle Delivery System for Deep Tumor Penetration (Angew. Chem. Int. Ed. 24/2014)

A nanoparticle delivery system enables deep tumor penetration. As R. Mo, C. Zhang et al. show in their Communication on page 6253 ff., pH-sensitive nanogels (small yellow spheres) accumulate at the tumor tissues (red cells). After internalization, the nanogels swell (large spheres) releasing the encapsulated chemotherapeutics (blue). The nanogel contracts (small yellow spheres), is liberated from the dead cells (grape-like cells), infects neighboring cancer cells nearer the center of the tumor, and the process is repeated.

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