Angewandte Chemie International Edition
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
October 10, 2001
Nobel Prize in Chemistry to Knowles, Noyori, and Sharpless
The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry for 2001 for the development of catalytic asymmetric synthesis, with one half jointly to William S. Knowles (*1917; St Louis, Missouri, USA) and Ryoji Noyori (*1938; Nagoya University, Chikusa, Nagoya, Japan) "for their work on chirally catalysed hydrogenation reactions" and the other half to K. Barry Sharpless the Scripps Research Institute, La Jolla, California, USA, "for his work on chirally catalysed oxidation reactions".
William S. Knowles discovered that it was possible to use transition metals to make chiral catalysts for hydrogenation. Ryoji Noyori has led the further development of this process to today's general chiral catalysts for hydrogenation. K. Barry Sharpless, on the other hand, is awarded half of the Prize for developing chiral catalysts for oxidation.
R. Noyori is also the chairman of the Editorial Board of Wiley-VCH's journal Advanced Synthesis & Catalysis and a member of Angewandte's International Advisory Board. K. B. Sharpless is a member of the Academic Advisory Board of Advanced Synthesis & Catalysis. Recent Reviews by the Prize winners in Angewandte include:
- Click Chemistry: Diverse Chemical Function from a Few Good Reactions
by Hartmuth C. Kolb, M. G. Finn, and K. Barry Sharpless
- Asymmetric Catalysis by Architectural and Functional Molecular Engineering: Practical Chemo- and Stereoselective Hydrogenation of Ketones
by Ryoji Noyori and Takeshi Ohkuma