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July 27, 2013
Stem Cells: Phenotype-Independent Effects of Retroviral Transduction in Human Dental Pulp Stem Cells
Obi Egbuniwe,* Andrew D. Grant, Tara Renton, and Lucy Di Silvio*
There has been considerable progress in the development of biopolymers that could impact directly on in vivo stem cell fate. Present-day biopolymers are being designed to mirror the well-described relationship existing between stem cells and the extracellular matrix. Researchers from London highlight the importance of the maintenance of cell viability and the development of human tissue-sourced stem cell lines. A better understanding of in vitro responses of these specialized cells to changes in their tightly regulated microenvironments will allow the utilization of their full therapeutic potential in biomimetic constructs
Macromol. Biosci., DOI: 10.1002/mabi.201300020
Other contributions to the article series on stem cells can be found here.