Macromolecular Symposia

Cover image for Vol. 374 Issue 1

August 16, 2013

NEW TECHNOLOGIES: Coupling Microreaction Technologies, Polymer Chemistry, and Processing to Produce Polymeric Micro and Nanoparticles with Controlled Size,

NEW TECHNOLOGIES: Coupling Microreaction Technologies, Polymer Chemistry, and Processing to Produce Polymeric Micro and Nanoparticles with Controlled Size,

Christophe A. Serra,* Bruno Cortese, Ikram Ullah Khan, Nicolas Anton, Mart H. J. M. de Croon, Volker Hessel, Tsutomu Ono, Thierry Vandamme

A hydrodynamic flow-focusing microfluidic device, coupled to a Tesla micromixer, enables rapid mixing and precipitation to form lipid–polymer nanoparticles. These nanoparticles have a PLGA hydrophobic core for drug encapsulation and a PEG hydrophilic shell with a lecithin layer in between. In the same way, lipid quantum dot nanoparticles can be formed with a core–shell structure.

Macromol. React. Eng. DOI: 10.1002/mren.201300101

Other contributions to the article series on new technologies in polymer reaction engineering can be found here.

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