Macromolecular Rapid Communications

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Recently Published Articles

  1. pH-Triggered Sustained Drug Delivery from a Polymer Micelle having the β-Thiopropionate Linkage

    Prithankar Pramanik, Debdatta Halder, Siddhartha Sankar Jana and Suhrit Ghosh

    Version of Record online: 22 JUL 2016 | DOI: 10.1002/marc.201600260

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    An effective design for pH-responsive polymeric micelle is demonstrated and utilized as a nanocontainer for intracellular sustained drug delivery in cancer cells. The strategy relies on slow hydrolysis of the as yet unexplored β-thiopropionate linkage connecting the hydrophobic chains to the polymer backbone.

  2. A pH-Responsive Hydrogel Based on a Tumor-Targeting Mesoporous Silica Nanocomposite for Sustained Cancer Labeling and Therapy

    Xin Chen and Zhongning Liu

    Version of Record online: 22 JUL 2016 | DOI: 10.1002/marc.201600261

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    A fluorescent mesoporous silica nanoconjugate end-capped with hyaluronic acid is developed, which displays great potential for tumor targeting, labeling, effective particle-to-hydrogel transformation in tumor environment, and controlled drug release in response to specific enzymes in tumor cells.

  3. Preparation of Janus Graphene Oxide (GO) Nanosheets Based on Electrostatic Assembly of GO Nanosheets and Polystyrene Microspheres

    Yongfang Yang, Lei Zhang, Xiaotian Ji, Lixin Zhang, Hefang Wang and Hanying Zhao

    Version of Record online: 22 JUL 2016 | DOI: 10.1002/marc.201600308

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    Materials with Janus structure are attractive for wide applications in chemistry and materials science. Although there are many syntheses of Janus particles in the literature, the synthesis of Janus graphene oxide (GO) nanosheets is rarely reported. A facile and versatile method for the synthesis of Janus GO nanosheets with different structures is proposed.

  4. Electron-Irradiated Polymer Brushes for Hollow Carbon Nanosphere Arrays

    Deul Kim, Artavazd Kirakosyan and Jihoon Choi

    Version of Record online: 22 JUL 2016 | DOI: 10.1002/marc.201600297

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    Polymer-grafted nanoparticles serve as a versatile platform for the synthesis of a hollow carbon nanoparticle array with a controlled microstructure. Electron irradiation plays a crucial role in maintaining a hexagonal array of hollow spheres during carbonization by the formation of stable networks between the polymer brushes.

  5. Ratiometric Fluorescent pH Probes Based on Glycopolymers

    Zhiyun Li, Pengshan Zhang, Wei Lu, Lun Peng, Yun Zhao and Gaojian Chen

    Version of Record online: 21 JUL 2016 | DOI: 10.1002/marc.201600242

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    A novel ratiometric fluorescent polymeric pH probe containing sugar and two different fluorescent moieties is prepared via the combination of reversible addition fragmentation chain transfer polymerization and thiol-ene reactions. The glycopolymer-based probe possessing the properties of serum-stability, cancer-targeting, and pH monitoring demonstrates great potential in cancer imaging and related applications.