Macromolecular Rapid Communications
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Editors: Kirsten Severing , Stefan Spiegel
Online ISSN: 1521-3927
Materials Science Weekly Newsletter
Recently Published Articles
- Tumor-Acidity Activated Surface Charge-Conversion of Polymeric Nanocarriers for Enhanced Cell Adhesion and Targeted Drug Release
Wei Wu, Jiantao Wang, Zaifu Lin, Xiuhua Li and Jianshu Li
Article first published online: 29 AUG 2014 | DOI: 10.1002/marc.201400362
The preparation of PLA-b-PAEMA/DMMA is discussed, since it can undergo a timely surface charge-conversion from negative to positive in response to the slight acidity of the tumor extracellular matrix. This can enhance tumor cell adhesion and targeted drug release for potential tumor therapy applications.
- Multi-Responsive Polypeptidosome: Characterization, Morphology Transformation, and Triggered Drug Delivery
Gang Liu, Linzhu Zhou, Yanfei Guan, Yue Su and Chang-Ming Dong
Article first published online: 29 AUG 2014 | DOI: 10.1002/marc.201400343
A novel multi-responsive polypeptide-based vesicle (polypeptidosome) is fabricated by controlling the structure transformation of one polypeptide block copolymer, and it presents the combined sensitivity of multiple physiological and clinic-related stimuli. The anticancer drug doxorubicin can be released in a controlled or on–off manner, enabling the polypeptidosome useful for on-demand nanomedicine and cancer therapy.
- One-Step Synthesis of Natural Silk Sericin-Based Microcapsules with Bionic Structures
Zhaogang Liu, Yurong Cai, Yaru Jia, Lin Liu, Xiangdong Kong, Subhas C. Kundu and Juming Yao
Article first published online: 28 AUG 2014 | DOI: 10.1002/marc.201400304
A one-step and environment-friendly method is developed to generate a series of silk sericin-based microcapsules with bionic structures depending on the change of Ca2+ concentration and agitation speed. The as-prepared cocoon-like microcapsules exhibit a pH-dependent stability with potential applications as controlled bioactive molecules loading and a release system.
- Supramolecular Adhesives to Hard Surfaces: Adhesion Between Host Hydrogels and Guest Glass Substrates Through Molecular Recognition
Yoshinori Takashima, Taiga Sahara, Tomoko Sekine, Takahiro Kakuta, Masaki Nakahata, Miyuki Otsubo, Yuichiro Kobayashi and Akira Harada
Article first published online: 27 AUG 2014 | DOI: 10.1002/marc.201400324
Hydrogels with cyclic host molecules selectively adhere to guest molecules modified glass substrates. Adhesion depends on the affinity of guest molecules with host molecules. External stimuli regulate the adhesion between host hydrogels and guest substrates. The host molecules of the host hydrogel precisely recognize the hydrophobicity of guest molecules on the glass substrates to create an adhesive force.
- Stable Cross-linked Fluorescent Polymeric Nanoparticles for Cell Imaging
Haiyin Li, Xiqi Zhang, Xiaoyong Zhang, Bin Yang, Yang Yang and Yen Wei
Article first published online: 27 AUG 2014 | DOI: 10.1002/marc.201400309
Stable cross-linked fluorescent polymeric nanoparticles are facilely prepared based on an aggregation-induced emission dye via a two-step polymerization including emulsion polymerization and subsequent anhydride cross-linking. These cross-linked polymers are easy to self-assemble into uniform nanoparticles that show high water dispersibility, intense red fluorescence, and excellent biocompatibility, making them promising for cell imaging applications.