Macromolecular Chemistry and Physics
© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
September 11, 2008
Functional Polymers: Functionality in ATRP: Functionalized Polymers and Nanogels
D. J. Siegwart, J. K. Oh, H. Gao, S. A. Bencherif, F. Perineau, A. K. Bohaty, J. O. Hollinger, and K. Matyjaszewski*
Functionality is one of the key attributes of atom transfer radical polymerization (ATRP). This feature can be exploited to prepare functional materials for a variety of different applications. Matyjaszewski and co-workers discuss in their latest publication in Macromolecular Chemistry and Physics how they utilized ATRP for the synthesis of well-controlled polymers functionalized with biotin, pyrene, and peptides via reaction at terminal hydroxyl groups. In addition, they found that ATRP and click chemistry offered an efficient route for the synthesis of telechelic di-biotin polymers. These general methods can be applied to the formation of different functional materials conjugated with proteins, dyes, nucleic acids, and drugs.
Macromol. Chem. Phys. DOI: 10.1002/macp.200800337