Macromolecular Chemistry and Physics

Cover image for Vol. 217 Issue 14

November 17, 2010

TALENT: Polymers for Control Freaks

TALENT: Polymers for Control Freaks

Laura Hartmann

Compared to biological polymers, most synthetic polymers utilized in medicine are often polydisperse in nature, statistically modified, and empirically optimized. Inherent distributions result in disperse structure-property relationships, which renders interpretation of the biological properties for such polymers difficult. Laura Hartmann presents in her Talent Article a novel synthetic strategy towards monodisperse, sequence-defined poly(amidoamine)s. Variations of the chemical structures are used to directly control the ability of such polycations to complex DNA and function as non-viral vectors. Her future work is expected to provide a deeper understanding of the interactions of fully synthetic with biological systems and using these interactions for the design of bioactive polymer-based materials.
This Talent Article is addtionally featured on MaterialsViews.

Macromol. Chem. Phys., DOI: 10.1002/macp.201000479

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