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  1. Tailoring Biomaterials for Cancer Immunotherapy: Emerging Trends and Future Outlook

    Chao Wang, Yanqi Ye, Quanyin Hu, Adriano Bellotti and Zhen Gu

    Version of Record online: 26 MAY 2017 | DOI: 10.1002/adma.201606036

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    Cancer immunotherapy has recently received tremendous attention and has created a paradigm shift in the treatment of cancer. An overview of the latest studies on tailoring biomaterials for enhancement of anticancer immunity is presented, including delivery of therapeutics to antigen-presenting cells, delivery of therapeutics to the tumor microenvironment, engineering of immune cells, and constructing immune scaffolds.

  2. Precise Two-Photon Photodynamic Therapy using an Efficient Photosensitizer with Aggregation-Induced Emission Characteristics

    Bobo Gu, Wenbo Wu, Gaixia Xu, Guangxue Feng, Feng Yin, Peter Han Joo Chong, Junle Qu, Ken-Tye Yong and Bin Liu

    Version of Record online: 26 MAY 2017 | DOI: 10.1002/adma.201701076

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    A new two-photon photosensitizer is synthesized and formulated into organic dots with aggregation-induced emission characteristics, large two-photon absorption cross section, high reactive-oxygen-species generation efficiency, and excellent photostability and biocompatibility, enabling in vitro cancer cell ablation and in vivo brain-blood-vessel closure with 5 µm precision under two-photon excitation.

  3. Hierarchically Enhanced Impact Resistance of Bioinspired Composites

    Grace X. Gu, Mahdi Takaffoli and Markus J. Buehler

    Version of Record online: 26 MAY 2017 | DOI: 10.1002/adma.201700060

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    An order of magnitude tougher than nacre, conch shells are known for being one of the toughest biological body armors. However, the complexity of the conch shell architecture creates a barrier to emulating its cross-lamellar structure in synthetic materials. In this paper, a 3D biomimetic conch shell prototype is presented, which can replicate the crack arresting mechanisms embedded in the natural architecture.

  4. Printable and Rewritable Full Block Copolymer Structural Color

    Han Sol Kang, Jinseong Lee, Suk Man Cho, Tae Hyun Park, Min Ju Kim, Chanho Park, Seung Won Lee, Kang Lib Kim, Du Yeol Ryu, June Huh, Edwin L. Thomas and Cheolmin Park

    Version of Record online: 26 MAY 2017 | DOI: 10.1002/adma.201700084

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    An ink-jet printable and rewritable full-color structural color display is obtained by the position- and concentration-controlled deposition of a single, colorless, water-based ink containing a reversible crosslinking agent, ammonium persulfate, onto a self-assembled block copolymer photonic-crystal film. The information is quickly written and erased over 50 times with resolution nearly equivalent to a office ink-jet printer.

  5. Wet-Chemical Synthesis of Hollow Red-Phosphorus Nanospheres with Porous Shells as Anodes for High-Performance Lithium-Ion and Sodium-Ion Batteries

    Jianbin Zhou, Xianyu Liu, Wenlong Cai, Yongchun Zhu, Jianwen Liang, Kailong Zhang, Yang Lan, Zhuoheng Jiang, Gongming Wang and Yitai Qian

    Version of Record online: 26 MAY 2017 | DOI: 10.1002/adma.201700214

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    Preparing nanostructured phosphorus by a chemical synthetic approach is always challenging. A wet solvothermal method is developed to fabricate hollow phosphorous nanospheres (HPNs) with porous shells via a gas-bubble-directed formation mechanism. More importantly, due to the merits of porous and hollow structures, HPNs reveal excellent electrochemical performance as anodes for lithium-ion and sodium-ion batteries.