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  1. Amorphizing of Cu Nanoparticles toward Highly Efficient and Robust Electrocatalyst for CO2 Reduction to Liquid Fuels with High Faradaic Efficiencies

    Yan-Xin Duan, Fan-Lu Meng, Kai-Hua Liu, Sha-Sha Yi, Si-Jia Li, Jun-Min Yan and Qing Jiang

    Version of Record online: 23 FEB 2018 | DOI: 10.1002/adma.201706194

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    An amorphous Cu catalyst displays superior catalytic activity toward electroreduction of CO2 with a remarkable selectivity for the reduction to liquid fuels (HCOOH andC2H6O) relative to a crystalline Cu catalyst.

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    Engineering Extracellular Vesicles with the Tools of Enzyme Prodrug Therapy

    Gregor Fuhrmann, Rona Chandrawati, Paresh A. Parmar, Timothy J. Keane, Stephanie A. Maynard, Sergio Bertazzo and Molly M. Stevens

    Version of Record online: 23 FEB 2018 | DOI: 10.1002/adma.201706616

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    Extracellular vesicles (EVs) are exploited as drug delivery vehicles but their therapeutic use may be limited due to off-target effects. To harness EVs' inherent properties and to couple them with site-specific drug delivery functions, EVs are incorporated into hydrogels and engineered with the tools of enzyme prodrug therapy. Local sustained release of antiinflammatory drugs is demonstrated in macrophage cell models.

  3. Quantum Emitters in Hexagonal Boron Nitride Have Spectrally Tunable Quantum Efficiency

    Andreas W. Schell, Mikael Svedendahl and Romain Quidant

    Version of Record online: 23 FEB 2018 | DOI: 10.1002/adma.201704237

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    Quantum emitters in hexagonal boron nitride are studied under excitation by light of different wavelengths. It is shown that single photons are emitted with different rates depending on the excitation energy and, in addition, the quantum efficiency changes. These findings are, for instance, important for future implementations of these emitters in quantum-information-processing schemes.

  4. Oxide Thin-Film Electronics using All-MXene Electrical Contacts

    Zhenwei Wang, Hyunho Kim and Husam N. Alshareef

    Version of Record online: 23 FEB 2018 | DOI: 10.1002/adma.201706656

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    MXene (Ti3C2) thin film is used for the first time as the electrical contacts (gate, source, and drain) for both n- and p-type thin-film transistors (TFT). The n- and p-type TFTs show reasonably good and balanced performance. A complementary metal oxide semiconductor device is further demonstrated, showing good static (high gain, excellent noise margin) and dynamic switching performance.

  5. Highly Augmented Drug Loading and Stability of Micellar Nanocomplexes Composed of Doxorubicin and Poly(ethylene glycol)–Green Tea Catechin Conjugate for Cancer Therapy

    Kun Liang, Joo Eun Chung, Shu Jun Gao, Nunnarpas Yongvongsoontorn and Motoichi Kurisawa

    Version of Record online: 23 FEB 2018 | DOI: 10.1002/adma.201706963

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    Self-assembled micellar nanocomplexes (MNCs) leverage the favorable interaction between the structurally similar green tea catechin (epigallocatechin-3-O-gallate) and small-molecular anticancer drug doxorubicin (DOX) to attain ultrahigh drug loading capacity and stability in circulation. These DOX-loaded MNCs demonstrate significant antitumor activity with attenuated toxicity, enabling a safe and effective strategy for cancer therapy.

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