18_04b/2006Inside Front Cover: Conducting-Polymer Nanotubes for Controlled Drug Release (Adv. Mater. 4/2006)

Martin and co-workers report on p. 405 that nanotubes formed from the conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT), as shown on the inside cover, can be used for the controlled release of anti-inflammatory drugs. The fabrication process includes electrospinning of a biodegradable polymer, either poly(L-lactide) or poly(lactide-co-glycolide), into which the required drug is incorporated, followed by electrochemical deposition of the conducting polymer around the drug-loaded electrospun nanofibers. Drug release from the nanotubes is achieved by external electrical stimulation of the nanotubes.

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