Advanced Materials

Cover image for Vol. 28 Issue 40

18_05/2006Cover Picture: A Micropatterned Hydrogel Platform for Chemical Synthesis and Biological Analysis (Adv. Mater. 5/2006)

A polymer hydrogel platform for peptide arrays compatible with both solid-phase peptide synthesis conditions and the aqueous environment essential for biological assays is reported on p. 655 by Ulijn and co-workers. Micropatterning followed by multiple-step peptide synthesis produces the peptide-functionalized poly(ethylene glycol)–polyamide “biochips” shown schematically on the cover. On-chip biological assays involving cells and enzymes provide proof-of-concept.

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