Advanced Materials

Cover image for Vol. 28 Issue 24

19_20b/2007Inside Front Cover: Hybrid Nanoparticles for Magnetic Resonance Imaging of Target-Specific Viral Gene Delivery (Adv. Mater. 20/2007)

The inside cover displays multifunctional “adenovirus-magnet” nanoparticles possessing target-specific infection, magnetic resonance imaging (MRI), and gene expression capabilities. These hybrid nanoparticles, reported by Jin-Suck Suh, Jinwoo Cheon, and co-workers on p. 3109 in the Special Section on Bionanotechnology, selectively target the Coxsackievirus B adenovirus receptor (CAR)-positive cells and deliver the gene of enhanced green fluorescent protein (eGFP), while simultaneously being imaged by MRI. These hybrid nanoparticles can be regarded as new probes for in vivo MRI tracking of targeted viral gene delivery, which is essential for next-generation diagnostics and therapeutics.

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