20_02/2008Cover Picture: Dynamic Imaging of Functionalized Multi-Walled Carbon Nanotube Systemic Circulation and Urinary Excretion (Adv. Mater. 2/2008)

Multiwalled carbon nanotubes (MWNTs) made highly water-dispersible by organic functionalization and radiolabeled with Indium-111 were shown to translocate through the kidney glomerular filter. On p. 225, multinational, multicenter research led by Kostas Kostarelos on dynamic imaging and tissue distribution of MWNTs in live animals is presented. The cover image presents a single plane single photon computed tomography whole body image of a rat following intravenous injection with the In-111 labeled MWNTs as seen through a 3D carbon NT projection. The radioactivity from carbon NTs was mainly localized in the kidneys, and accumulated in the bladder before clearance in the urine.

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